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M94A0686.TXT
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1994-10-21
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Document 0686
DOCN M94A0686
TI Perinatal exposure to HIV in Australia 1982-1993.
DT 9412
AU Cruickshank M; Ziegler JB; McDonald A; Prince of Wales Children's
Hospital, Randwick.
SO Annu Conf Australas Soc HIV Med. 1993 Oct 28-30;5:39 (abstract no. TE4).
Unique Identifier : AIDSLINE ASHM5/94348969
AB OBJECTIVE: To describe the epidemiology of perinatal HIV exposure and
transmission in Australia. METHODS: A registry of all cases of perinatal
exposure to HIV was established using data retrieved retrospectively to
test for possible factors affecting transmission rate, maternal and
infant variables were examined using Chi square. RESULTS: Between 1982
and June 1993, 72 babies were reported as perinatally exposed to HIV
infection. Six infants have indeterminate status. Of the 66 children for
whom infection status could be determined, 22 (33%) have acquired HIV
infection. Infants horn to mothers infected as the result of injecting
drug use had a 47% transmission rate. Those infants born to mothers from
Pattern II countries had a transmission rate of 83% (p = 0.02). Among 19
infants known to have been breastfed, 10 are infected (52%). Among 29
infants who were never breastfed, 7 are infected (24%) (p = 0.04). No
other factors were noted. CONCLUSION: The perinatal HIV register appears
informative and prospective data acquisition is advocated.
DE Australia/EPIDEMIOLOGY Breast Feeding Cross-Sectional Studies Female
Human HIV Infections/EPIDEMIOLOGY/*TRANSMISSION Incidence Infant,
Newborn Pregnancy Pregnancy Complications, Infectious/*EPIDEMIOLOGY
Registries/STATISTICS & NUMER DATA Risk Factors MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).